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Important Safety Information for BAXFENDY™ (baxdrostat)

BAXFENDY may cause side effects, including:

  • Increased potassium levels in your blood (hyperkalemia). Your risk of developing hyperkalemia is increased if you are 65 years of age or older, have diabetes or kidney problems or take other medicines that can increase potassium levels. Talk to your healthcare provider before using potassium supplements or salt substitutes that contain potassium during your treatment with BAXFENDY
  • Decreased sodium levels in your blood (hyponatremia). Your risk of developing hyponatremia is increased if you already have a low sodium blood level or take medicines that can cause hyponatremia. Tell your healthcare provider right away if you have any symptoms of low sodium levels during treatment. Symptoms of low sodium levels in your blood may include unusual fatigue, dizziness, headache, shortness of breath, or confusion

Your healthcare provider will check potassium and sodium levels in your blood before treatment with BAXFENDY and periodically during your treatment. Your healthcare provider may temporarily stop your treatment with BAXFENDY if you develop high potassium or low sodium levels in your blood.

The most common side effect is hyperkalemia. Other common side effects include low blood pressure, dizziness, and muscle spasms.

Before taking BAXFENDY, tell your healthcare provider if you:

  • have high potassium levels in your blood
  • have kidney problems
  • have diabetes
  • are pregnant or plan to become pregnant. It is not known if BAXFENDY can harm your unborn baby
  • are breastfeeding or plan to breastfeed. It is not known if BAXFENDY passes into your breast milk. Talk to your healthcare provider about the best way to feed your baby during treatment with BAXFENDY
  • about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and supplements

Approved Uses for BAXFENDY

BAXFENDY is a prescription medicine used along with other blood pressure medicines to treat high blood pressure (hypertension) in adults whose blood pressure is not well controlled with other medicines.

Please see Prescribing Information and Patient Information for BAXFENDY.

You may report side effects related to AstraZeneca products .

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This product information is intended for US Consumers only.

BAXFENDY is a trademark of the AstraZeneca group of companies. All other trademarks are property of their respective owners.

©2026 AstraZeneca. All rights reserved.

US-108917 Last Updated 5/26

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